People using drug Mounjaro sustain weight loss over three years, trial finds

People who use the drug Mounjaro are able to sustain weight loss for three years, data from a trial suggests.Mounjaro, nicknamed the “King Kong” of weight loss drugs, contains tirzepatide and is self-administered in once-a-week injections.It works by mimicking two hormones called GLP-1 and GIP, resulting in appetite suppression, increased production of insulin, greater insulin sensitivity and a reduction in the rate at which food is emptied from the stomach. The medication is available for weight loss to some people on the NHS and it can also be bought privately with a prescription.Scientists at Eli Lilly, the company that makes Mounjaro, along with academic researchers have released two analyses of data from a three-year trial known as Surmount-1, throwing fresh light on the medication’s longer-term use. One analysis looked at trajectories of weight loss, the second at rebound after initial weight reduction.The results, which are to be presented at the European Congress on Obesity in...