Serie A official Week 16 line-ups: Como vs. Milan
Milan try to keep up with leaders Inter as Rafael Leao and Christopher Nkunku lead the way in a trip to Como, where Nico Paz and Tasos Douvikas target sixth place.
It kicks off at the Stadio Sinigaglia at 19.45 GMT (20.45 CET).
These are the rescheduled Week 16 fixtures, moved from December due to the Supercoppa Italiana commitments.
They already started last night with Inter beating Lecce 1-0 and Napoli held 0-0 by Parma, opening up a significant gap at the top of the Serie A table.
It means Milan have an opportunity to stay within three points of the leaders with a victory, but Como also know a win would put them within two points of fourth.
A boost is badly needed for Max Allegri, who is coming off back-to-back 1-1 draws against Genoa and Fiorentina.
Strahinja Pavlovic needed stitches to his head and Niclas Fullkrug fractured a toe in Florence, but the former West Ham United striker is still fit for the bench.
Santiago Gimenez remains the only long-term absentee, with Christian Pulisic not at 100 per cent, so Leao partners Nkunku upfront.
Fikayo Tomori returns from suspension in defence, with Luka Modric and Adrien Rabiot also back.
Como saw their run of three consecutive victories stalled by a 1-1 draw against Bologna on Saturday.
Jacobo Ramon is back from his ban, though Assane Diao, Jayden Addai, Edoardo Goldaniga and ex-Milan striker Alvaro Morata are all injured.
Nico Paz is the star man in attack with Douvikas and Martin Baturina, as Cesc Fabregas always wants an attacking and positive approach.
Como are unbeaten at home so far this season.
Como vs. Milan line-ups
Como: Butez; Van Der Brempt, Ramon, Kempf, Moreno; Perrone, Da Cunha; Vojvoda, Paz, Baturina; Douvikas
Milan: Maignan; Tomori, Gabbia, De Winter; Saelemaekers, Fofana, Modric, Rabiot, Bartesaghi; Nkunku, Leao