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Opening odds for the first round of the 2025 NCAA men’s basketball tournament

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Photo by Luke Hales/Getty Images

The NCAA men’s basketball tourney field is set. We’re posting odds as they go live.

March Madness is upon us! The NCAA men’s basketball tournament selection committee has finalized the bracket and CBS has unveiled every matchup in the First Four and the first round. We’ve provided the full list of matchups below and added in opening odds as FanDuel Sportsbook made them available.

Notably, we’re seeing considerable early movement in the lines. The most notable saw Memphis open as a 1.5-point favorite against Colorado State, but early money has moved it so the Rams are now a 3.5-point favorite as of 7:15 p.m. ET. The numbers below reflect where they opened, not where they currently stand.

The tournament opens with the First Four on Tuesday, March 18 and Wednesday, March 19. The first round then kicks off on Thursday, March 20. The national champion will be crowned on April 7 at the Alamodome in San Antonio, Texas. Duke enters the tournament as the favorite, installed at +340 ahead of the Selection show. Florida follows at +440 and SEC running mate Auburn is installed at +480.

First Four matchups

#11 San Diego State vs. #11 North Carolina

Point spread: UNC -2.5
Total: 145.5
Moneyline: UNC -150, SDSU +125

#11 Texas vs. #11 Xavier

Point spread: Xavier -1.5
Total: 149.5
Moneyline: Xavier -113, Texas -106

#16 Alabama State vs. #16 Saint Francis (PA)

Point spread: Alabama State -4.5
Total: Alabama 142.5
Moneyline: Alabama State -162, Saint Francisc +134

#16 American vs. #16 Mount St. Mary’s

Point spread: American -3.5
Total: 133.5
Moneyline: American -125, Mount St. Mary’s +105

South region

#1 Auburn vs. #16 Alabama State/Saint Francis (PA)

Point spread: TBD
Total: TBD
Moneyline: TBD

#8 Louisville vs. #9 Creighton

Point spread: Louisville -2.5
Total: 145.5
Moneyline: Louisville -138, Creighton +115

#5 Michigan vs. #12 UC San Diego

Point spread: Michigan -3.5
Total: 142.5
Moneyline: Michigan -160, UCSD +132

#4 Texas A&M vs. #13 Yale

Point spread: Texas A&M -7.5
Total: 141.5
Moneyline: Texas A&M -315, Yale +250

#6 Ole Miss vs. #11 San Diego State/North Carolina

Point spread: TBD
Total: TBD
Moneyline: TBD

#3 Iowa State vs. #14 Lipscomb

Point spread: ISU -14.5
Total: 143.5
Moneyline: Iowa State -1250, Lipscomb +760

#7 Marquette vs. #10 New Mexico

Point spread: Marquette -3.5
Total: 154.5
Moneyline: Marquette -178, New Mexico +146

#2 Michigan State vs. #15 Bryant

Point spread: MSU -17.5
Total: 150.5
Moneyline: MSU -4000, Bryant +1400

East region

#1 Duke vs. #16 American/Mount St. Mary;s

Point spread: TBD
Total: TBD
Moneyline: TBD

#8 Mississippi State vs. #9 Baylor

Point spread: Baylor -1.5
Total: 141.5
Moneyline: Baylor -113, Mississippi State -106

#5 Oregon vs. #12 Liberty

Point spread: Oregon -6.5
Total: 141.5
Moneyline: Oregon -250, Liberty +202

#4 Arizona vs. #13 Akron

Point spread: Arizona -14.5
Total: 165.5
Moneyline: Arizona -1200, Akron +720

#6 BYU vs. #11 VCU

Point spread: BYU -2.5
Total: 143.5
Moneyline: BYU -137, VCU +114

#3 Wisconsin vs. #14 Montana

Point spread: Wisconsin -17.5
Total: 148.5
Moneyline: Wisconsin -3500, Montana +1280

#7 Saint Mary’s vs. #10 Vanderbilt

Point spread: SMC -4.5
Total: 136.5
Moneyline: SMC -192, Vanderbilt +158

#2 Alabama vs. #15 Robert Morris

Point spread: Alabama -20.5
Total: 164.5
Moneyline: Alabama -4000, Robert Morris +1400

Midwest region

#1 Houston vs. #16 SIU-Edwardsville

Point spread: Houston -28.5
Total: 127.5
Moneyline: Houston -50000, SIUE +4000

#8 Gonzaga vs. #9 Georgia

Point spread: Gonzaga -6.5
Total: 151.5
Moneyline: Gonzaga -295, Georgia +235

#5 Clemson vs. #12 McNeese

Point spread: Clemson -8.5
Total: 136.5
Moneyline: Clemson -320, McNeese +255

#4 Purdue vs. #13 High Point

Point spread: Purdue -10.5
Total: 154.5
Moneyline: Purdue -430, High Point +330

#6 Illinois vs. #11 Texas/Xavier

Point spread: TBD
Total: TBD
Moneyline: TBD

#3 Kentucky vs. #14 Troy

Point spread: Kentucky -11.5
Total: 152.5
Moneyline: Kentucky -780, Troy +530

#7 UCLA vs. #10 Utah State

Point spread: UCLA -4.5
Total: 142.5
Moneyline: UCLA -205, Utah State +168

#2 Tennessee vs. #15 Wofford

Point spread: Tennessee -18.5
Total: 131.5
Moneyline: Tennessee -4000, Wofford +1400

West region

#1 Florida vs. #16 Norfolk State

Point spread: Florida -26.5
Total: 154.5
Moneyline: Florida -30000, Norfolk State +4000

#8 UConn vs. #9 Oklahoma

Point spread: UConn -4.5
Total: 146.5
Moneyline: UConn -194, Oklahoma +158

#5 Memphis vs. #12 Colorado State

Point spread: Memphis -1.5
Total: 143.5
Moneyline: Memphis -113, Colorado State -106

#4 Maryland vs. #13 Grand Canyon

Point spread: Maryland -10.5
Total: 151.5
Moneyline: Maryland -690, Grand Canyon +480

#6 Missouri vs. #11 Drake

Point spread: Missouri -6.5
Total: 133.5
Moneyline: Missouri -285, Drake +230

#3 Texas Tech vs. #14 UNC Wilmington

Point spread: TT -15.5
Total: 141.5
Moneyline: TT -2300, UNCW +1060

#7 Kansas vs. #10 Arkansas

Point spread: Kansas -5.5
Total: 146.5
Moneyline: Kansas -225, Arkansas +184

#2 St. John’s vs. #15 Omaha

Point spread: St. John’s -16.5
Total: 147.5
Moneyline: St. John’s -3000, Omaha +1280

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