UCL researchers develop groundbreaking therapy for a common cause of high blood pressure

University College LondonFeb 25 2025A minimally invasive therapy that has the potential to transform treatment of a common cause of high blood pressure, has been developed by researchers at UCL, Queen Mary University of London and Barts Health.High blood pressure affects around one in three adults in the UK, with estimates suggesting that at least one in twenty cases are caused by a hormonal condition called primary aldosteronism. However, only a small percentage of those affected by primary aldosteronism are ever diagnosed.The condition occurs when tiny benign nodules (abnormal tissue growths) in one or both adrenal glands produce excess aldosterone, a hormone that raises blood pressure by increasing salt levels in the body. Patients with primary aldosteronism often do not respond well to standard blood pressure medications and face higher risks of heart attack, stroke, and kidney failure.Findings from the FABULAS study, published in The Lancet, describe initial results for Targeted T...