Is Walgreens Open or Closed on Thanksgiving Day 2025?

Many shoppers rely on Walgreens for its convenience, and its pharmacy. But will Walgreens be open or closed on Thanksgiving Day 2025?

It depends on the type of Walgreens store. "Most Walgreens locations will be closed on Thanksgiving," according to USA Today. However, the company's website says, "Most Walgreens stores will be closed Thanksgiving Day. 24-hour locations will remain open."

What about pharmacies? "24-hour locations and pharmacies will remain open; however, non-24-hour locations will be closed," USA Today noted, adding, "Customers are encouraged to call their nearest Walgreens location or use the store locator function on the company's website to check for specific hours." The store locator function allows customers to search for 24-hour locations.

What about CVS? According to USA Today, CVS pharmacies will be open on Thanksgiving Day, although possibly with reduced hours. Stores like Walmart, Costco, Target, and Home Depot are closed on Thanksgiving Day 2025, the newspaper noted.

Many communities rely on a local Walgreens store. There are more than 8,000 Walgreen pharmacies located throughout the U.S., according to ScrapeHero. "The state and territory with the most number of Walgreens locations in the US is Florida, with 787 pharmacies, which is about 10% of all Walgreens pharmacies in the US," according to ScrapeHero.

Thanksgiving Became a National Holiday Thanks to the Work of Sara Josepha Hale

President James Madison "proclaimed a day of Thanksgiving to be held on April 13, 1815, the last such proclamation issued by a President until Abraham Lincoln did so in 1862," according to the Smithsonian.

"Most of the credit for the establishment of an annual Thanksgiving holiday may be given to Sarah Josepha Hale. Editor of Ladies Magazine and Godey's Lady's Book, she began to agitate for such a day in 1827 by printing articles in the magazines," the Smithsonian explains.

"She also published stories and recipes, and wrote scores of letters to governors, senators, and presidents. After 36 years of crusading, she won her battle," the institution wrote. "On October 3, 1863, buoyed by the Union victory at Gettysburg, President Lincoln proclaimed that November 26, would be a national Thanksgiving Day, to be observed every year on the fourth Thursday of November."

According to the Smithsonian, "Only twice has a president changed the day of observation. President Franklin D. Roosevelt, in order to give depression-era merchants more selling days before Christmas, assigned the third Thursday to be Thanksgiving Day in 1939 and 1940. But he was met with popular resistance, largely because the change required rescheduling Thanksgiving Day events such as football games and parades. In 1941, a Congressional Joint Resolution officially set the fourth Thursday of November as a national holiday for Thanksgiving."

The Smithsonian noted: "Most Americans are familiar with the Pilgrims' Thanksgiving Feast of 1621, but few realize that it was not the first festival of its kind in North America. Long before Europeans set foot in the Americas, native peoples sought to ensure a good harvest with dances and rituals such as the Green Corn Dance of the Cherokees."

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